News

First results from Moderna COVID-19 vaccine may take two more months, analysts say

First results from Moderna COVID-19 vaccine may take two more months, analysts say
Business
An experimental vaccine for the novel coronaviru s developed by Moderna Inc. was dosed in the first patient earlier this month and it seems a first look at the results could come in a little over two months, at least according to Goldman Sachs.

“First data in the near-term (at least 2+ months),” from the initial dosing, analyst Salveen Richter wrote in a research report after a call with executives from the biotech company.

Moderna announced dosing the first patient in the early stage study of mRNA-1273 on March 16. The trial in 45 healthy people is being run by the U.S. National Institutes of Health’s National Institute of Allergy and Infectious Diseases, with patients in the study getting two doses of the vaccination 28 days apart.

While NIH has control over when results will be disclosed, “management guided to data availability in the near-term and suggested that the first data release will likely include a full cohort (>3-5 patients) to reflect the totality of the scientific picture,” Richter said.

Moderna shares have been outperforming the market since late February as investors look to drugmakers to come up with solutions to the global epidemic, and hope to see stronger immune response and a clean safety profile as mRNA-1273 doses escalate. “An ambiguous response, potentially due to low dose levels or if the vaccine is not as well tolerated as other vaccines, may require additional optimization,” Richter said. The stock rose as much as 5.1 per cent on Thursday.

On Monday, the Cambridge, Mass.-based company told investors that the vaccine could be available to some patients, likely health-care workers, under emergency use authorization in the fall, depending on the results and regulators. The NIH and the Food and Drug Administration have been signalling that getting a vaccine to the broader public would likely take at least a year. Moderna has already been preparing for the second stage of clinical testing and intends to work with the FDA and other organizations to be ready for more trials.

Moderna didn’t immediately respond to requests for comment.

Moderna is not the only vaccine maker racing to find a preventative treatment for the disease. An executive from Inovio Pharmaceuticals Inc. went on “60 Minutes” over the weekend to tell viewers that it would start a large mid-stage study by the end of the year, although the company had to yet to start testing its vaccine in humans.

There are no guarantees that either of the vaccines will work. The history of developing treatments and vaccines for outbreaks has been fraught with failure and has resulted in few pay offs for drug developers.
Read more on Toronto Star
News Topics :
Similar Articles :
Top Stories
WASHINGTON A team of scientists jostled for a view of the lab dish, staring impatiently for the first clue that an experimental vaccine against the new coronavirus...
Science
Update, 25 March Among dozens of vaccine candidates now under development to fight the new coronavirus, Moderna Therapeuticss mRNA 1273 was the first to emerge. The company is speeding the vaccine...
Science
Earlier this year, Paolo Martini, who heads rare disease research at the closely scrutinized biotech company Moderna Therapeutics in Cambridge, Massachusetts, visited the Middle East. He met with doctors who...
Science
Studying the 3D structures of the RSV surface protein, Graham discovered that the dynamic molecule had different orientations before and after fusing with the cell. Only the pre fusion state, it...
World
CHICAGO Reuters Drugmakers are working as quickly as possible to develop a vaccine to combat the rapidly spreading coronavirus that has infected more than 100, 000 people worldwide. FILE PHOTO...